Synthetic Neurobiology Group

Ed Boyden, Ph.D., Principal Investigator

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Resources

Optogenetic molecular reagents enabling control of targeted neurons and biological functions with light

  • ArchT: Archaerhodopsin from Halorubrum sp. TP009: genetically-encoded reagent for high-performance yellow/green-light neural silencing, 3.5x more light sensitive than Arch

  • Arch: Archaerhodopsin from H. sodomense: genetically-encoded reagent for high-performance yellow/green-light neural silencing

  • Mac: opsin from L. maculans: genetically-encoded reagent for blue/green-light neural silencing

  • ChR2-2A-Halo: Channelrhodopsin-halorhodopsin gene fusions: bi-directional neural control with two different colors of light

  • Halo/NpHR: Halorhodopsin from N. pharaonis: genetically-encoded reagent for yellow-light neural hyperpolarization

  • ChR2: Channelrhodopsin-2 from C. reinhardtii: genetically-encoded reagent for blue-light neural activation

  • Accessory reagents for optogenetics

  • Lentivirus production for high-titer, cell-specific, in vivo neural labeling

Optogenetic hardware and systems for control of neural circuits and biological functions with light

  • Versatile, but Manually-Assembled, Optical Fiber/Laser System for In Vivo (Multicolor) Light Delivery for Brain Neuromodulation

  • Very Simple Off-The-Shelf Laser and Viral Injector Systems for In Vivo Optical Neuromodulation

Recording and data analysis technologies for observing and analyzing neural circuit dynamics

  • Autopatcher.org: In Vivo Robotics, for Automatic Recording of Neurons in the Live Brain

Home » Resources

Optogenetic molecular reagents enabling control of targeted neurons and biological functions with light

ArchT: Archaerhodopsin from Halorubrum sp. TP009: genetically-encoded reagent for high-performance yellow/green-light neural silencing, 3.5x more light sensitive than Arch

Arch: Archaerhodopsin from H. sodomense: genetically-encoded reagent for high-performance yellow/green-light neural silencing

Mac: opsin from L. maculans: genetically-encoded reagent for blue/green-light neural silencing

ChR2-2A-Halo: Channelrhodopsin-halorhodopsin gene fusions: bi-directional neural control with two different colors of light

Halo/NpHR: Halorhodopsin from N. pharaonis: genetically-encoded reagent for yellow-light neural hyperpolarization

ChR2: Channelrhodopsin-2 from C. reinhardtii: genetically-encoded reagent for blue-light neural activation

Accessory reagents for optogenetics

Lentivirus production for high-titer, cell-specific, in vivo neural labeling

Optogenetic hardware and systems for control of neural circuits and biological functions with light

Versatile, but Manually-Assembled, Optical Fiber/Laser System for In Vivo (Multicolor) Light Delivery for Brain Neuromodulation

Very Simple Off-The-Shelf Laser and Viral Injector Systems for In Vivo Optical Neuromodulation

Recording and data analysis technologies for observing and analyzing neural circuit dynamics

Autopatcher.org: In Vivo Robotics, for Automatic Recording of Neurons in the Live Brain

Copyright 1995-2013, Ed Boyden esb@media.mit.edu