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Xiaofeng Qian

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Xiaofeng, during his time in the lab as a postdoctoral fellow, worked on novel opsin discovery, and viral targeting of opsins to specific cell types. After finishing his work in the lab, he entered a program to study the discipline of statistical sciences.

Projects

Optogenetic molecular reagents enabling control of the activity of targeted neurons and biological functions with light

Publications

Chow, B. Y.*, Han, X.*, Dobry, A. S., Qian, X., Chuong, A. S., Li, M., Henninger, M. A., Belfort, G. M., Lin, Y., Monahan, P. E., Boyden, E. S. (2010) High-performance genetically targetable optical neural silencing by light- driven proton pumps, Nature 463:98-102. (* co-first authors)
Boyden, E. S., Han, X., Talei Franzesi, G., Chan, S., Bernstein, J., Qian, X., Li, M. (2009) "New Techniques for Investigating Brain Rhythms: Optical Neural Control and Multielectrode Recording," In: Rhythms of the Neocortex: Where Do They Come From and What Are They Good For? (Kopell N., ed.) pp. 65-75. Washington, DC: Society for Neuroscience.
Han, X.*, Qian, X., Bernstein, J.G., Zhou, H.-H., Talei Franzesi, G., Stern, P., Bronson, R.T., Graybiel, A.M., Desimone, R., and Boyden, E.S.* (2009) Millisecond-Timescale Optical Control of Neural Dynamics in the Nonhuman Primate Brain, Neuron 62(2): 191-198. (* co-corresponding authors)
Chow B, Han X, Qian X and Boyden E (2009). High-performance halorhodopsin variants for improved genetically-targetable optical neural silencing. Frontiers in Systems Neuroscience. Conference Abstract: Computational and systems neuroscience. doi: 10.3389/conf.neuro.10.2009.03.347
Boyden E, Franzesi G T, Qian X, Li M, Han X, Borgers C, Kopell N J, Le Beau F and Whittington M A (2009). Probing mechanisms of gamma rhythmogenesis with cell type-specific optical neural control. Frontiers in Systems Neuroscience. Conference Abstract: Computational and systems neuroscience. doi: 10.3389/conf.neuro.10.2009.03.299
Bernstein, J. G., Han, X., Henninger, M. A., Ko, E. Y., Qian, X., Franzesi, G. T., McConnell, J. P., Stern, P., Desimone, R., and Boyden, E. S. (2008) Prosthetic systems for therapeutic optical activation and silencing of genetically-targeted neurons. Proc Soc Photo Opt Instrum Eng, 6854:68540H.

Synthetic Neurobiology Group

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Alumni - UROPs and Other Undergraduate Researchers